Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCPEP1 All Species: 41.21
Human Site: T104 Identified Species: 60.44
UniProt: Q9HB40 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB40 NP_067639.1 452 50831 T104 D L K P R K T T W L Q A A S L
Chimpanzee Pan troglodytes XP_001172174 452 50766 T104 D L K P R K T T W L Q A A S L
Rhesus Macaque Macaca mulatta XP_001104815 452 50613 T104 D L K P R K T T W L Q A A S L
Dog Lupus familis XP_537688 477 53125 T129 D L K P R R T T W L Q S A S L
Cat Felis silvestris
Mouse Mus musculus Q920A5 452 50948 T104 Q L K P R N T T W L Q W A S L
Rat Rattus norvegicus Q920A6 452 51156 T104 R L K P R N T T W L Q W A S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521733 560 62210 T210 E L K P R T T T W V Q A A S I
Chicken Gallus gallus NP_001012821 446 49959 W94 L K P R N T T W L Q A A S I L
Frog Xenopus laevis NP_001088737 443 49367 N97 S T W V Q A V N L L F V D N P
Zebra Danio Brachydanio rerio NP_956486 445 49600 S97 D L K L R E T S W V R A A S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392686 435 48876 S97 D L R P R N F S W V K D Y N I
Nematode Worm Caenorhab. elegans NP_872130 445 50095 T95 N G S D N P A T W L Q V A D M
Sea Urchin Strong. purpuratus XP_785691 470 52220 T102 N Q N P R N T T W V S V A N I
Poplar Tree Populus trichocarpa XP_002313552 489 53783 T109 Y L K P R N S T W L Q V A D L
Maize Zea mays NP_001148149 464 50034 L103 K P R A T T W L A K A D L L F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67Y83 461 51734 L103 K P R N S T W L K K A D L L F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96 82.8 N.A. 82 82.7 N.A. 60.7 65.9 65.9 62.8 N.A. N.A. 42 41.8 47.8
Protein Similarity: 100 99.3 99.1 88.2 N.A. 90.7 91.8 N.A. 70.7 78.9 77.2 77.6 N.A. N.A. 59.2 58.6 63.6
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 73.3 20 6.6 60 N.A. N.A. 33.3 33.3 40
P-Site Similarity: 100 100 100 100 N.A. 80 80 N.A. 93.3 26.6 20 93.3 N.A. N.A. 73.3 46.6 66.6
Percent
Protein Identity: 42.7 45 N.A. 42.9 N.A. N.A.
Protein Similarity: 57.2 58.6 N.A. 60.7 N.A. N.A.
P-Site Identity: 66.6 0 N.A. 0 N.A. N.A.
P-Site Similarity: 73.3 6.6 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 7 7 0 7 0 19 38 69 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 38 0 0 7 0 0 0 0 0 0 0 19 7 13 0 % D
% Glu: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 7 0 0 0 13 % F
% Gly: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 19 % I
% Lys: 13 7 57 0 0 19 0 0 7 13 7 0 0 0 0 % K
% Leu: 7 63 0 7 0 0 0 13 13 57 0 0 13 13 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 13 0 7 7 13 32 0 7 0 0 0 0 0 19 0 % N
% Pro: 0 13 7 63 0 7 0 0 0 0 0 0 0 0 7 % P
% Gln: 7 7 0 0 7 0 0 0 0 7 57 0 0 0 0 % Q
% Arg: 7 0 19 7 69 7 0 0 0 0 7 0 0 0 0 % R
% Ser: 7 0 7 0 7 0 7 13 0 0 7 7 7 50 0 % S
% Thr: 0 7 0 0 7 25 63 63 0 0 0 0 0 0 0 % T
% Val: 0 0 0 7 0 0 7 0 0 25 0 25 0 0 7 % V
% Trp: 0 0 7 0 0 0 13 7 75 0 0 13 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _